Skin & Topical

The bladder expresses CB1 and CB2 receptors throughout its tissue layers, and the Pagano group found CBG the most effective of five cannabinoids tested in reducing bladder contractility — what that finding means, what it doesn't, and where the research stands.

Research Article · Skin Topical

Recurrent vaginal candidiasis and urinary tract infections affect large numbers of women and resist easy resolution — both involve organisms against which cannabinoids have documented in vitro activity. What that activity means and what it cannot establish.

Research Article · Skin Topical

CBG reduced abnormal skin cell proliferation in keratinocyte cell cultures — what the Wilkinson study found, the mechanism it identified, and what cell culture evidence can and cannot establish about living skin.

Research Article · Skin Topical

The skin is not simply a surface — it is a layered organ with its own endocannabinoid system. Understanding the receptor landscape across skin tissue types provides the mechanistic foundation for reading CBG skin research accurately.

Research Article · Skin Topical

A plain account of how cannabinoids behave in skin tissue, what the research has established about delivery, and why topical and oral preparations work through different mechanisms.

Experience Article · Skin Topical

What the research shows about CB2 receptors in synovial tissue, how much topical preparations can reasonably reach, and what that means for the person using them.

Experience Article · Skin Topical

For the person with eczema, psoriasis, or chronic skin inflammation that conventional treatment has managed but not resolved — what the cannabinoid research has examined in skin tissue.

Experience Article · Skin Topical